Nodular Cystic Basal Cell Carcinoma of the Trunk: a Diagnostic Dilemma in an Unsuspecting Youth

Authors

  • Bhavna Garg Department of Pathology, Dayanand Medical College & Hospital, Tagore Nagar, Ludhiana, Punjab, India
  • Dilpreet Kaur Department of Pathology, Dayanand Medical College & Hospital, Tagore Nagar, Ludhiana, Punjab, India
  • Gursheen Kaur Senior Resident Department of Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, UP
  • Neena Sood Professor & Head, Department of Pathology, Dayanand Medical College & Hospital, Tagore Nagar, Ludhiana, Punjab, India
  • Ruchita Tyagi Department of Pathology, Dayanand Medical College & Hospital, Tagore Nagar
  • Sunil Gupta Professor & Head, Department of Skin & Venereal diseases, Dayanand Medical College & Hospital, Tagore Nagar, Ludhiana, Punjab, India
Abstract:

Basal cell carcinoma (BCC) commonly affects the elderly and is mostly confined to the head and neck region. Only 10% of all cases occur on the trunk. We presented a case of bullous lesion on the abdomen in a young male, initially diagnosed by clinicians as a vascular nevus. Histopathological examination and immunohistochemistry (IHC) revealed it to be Nodular cystic variant of BCC. This rare variant of BCC morphologically resembles benign skin adnexal tumor of Eccrine syringofibroadenoma. Ber Ep4 positivity on IHC established the correct diagnosis. This case highlights that nodular cystic variant of BCC can be a diagnostic dilemma for clinicians and pathologists.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

Nodular fasciitis: a diagnostic dilemma.

A 65 year old man presented with a right upper cervical mass. A diagnosis of pleomorphic adenoma was reported on fine needle aspiration cytology (FNAC). CT scan however reported an intramuscular sternocleidomastoid swelling. The tumor was excised and a diagnosis of nodular fasciitis was made. It is important to be aware of this diagnosis and that FNAC reports may mimic that of a pleomorphic ade...

full text

Basal cell carcinoma of the lower extremities

Background: Basal cell carcinoma (BCC), the most common form of skin cancer, usually occurs in the sun-exposed areas of the body like head and neck, yet is also seen in unexpected sites. Myriad studies have mentioned a lower limb BCC incidence rate of 1.5-13.5%.Methods: The present retrospective cross-sectional study was conducted on 650 BCC patients, who were referred to the dermatology tumor ...

full text

Basal cell carcinoma in a young woman: A case report

Basal cell carcinoma (BCC) is a malignant tumor of epithelial cells that is composed of cells similar to those in the basal area of the epidermis and its appendages. Ninety- five percent of individuals with BCC are between 40 and 79 years old. It rarely occurs in younger individuals. Herein, a 20- year- old woman with type III skin, who had a BCC on her chin is presented. Since the clinic...

full text

The Usefulness of CD10 in Distinguishing between Cutaneous Basal Cell Carcinoma and Squamous Cell Carcinoma

Background & Objectives:  CD10 is a cell surface enzyme with metalloendopeptidase activity, also known as Common Acute Lymphoblastic Leukaemia Antigen, which mainly serves as a marker for acute lymphoblastic leukemia (ALL). To date and to the best of our knowledge, only few comparative immunohistochemical studies have assessed CD10 expression in cutaneous epithelial neoplasms. Our goal was to d...

full text

Evaluation of Diagnostic Values of EMA and Ber-Ep4 in Distinction between Basal Cell Carcinoma and Squamous Cell Carcinoma of the Skin

Background and Objective: Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) are two common tumors of the skin. In some cases, distinction between BCC and SCC can be difficult. This study aimed to clarify this uncertainty through immunohistochemical analysis. In this respect, epithelial membran...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 12  issue 4

pages  410- 412

publication date 2017-12-01

By following a journal you will be notified via email when a new issue of this journal is published.

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023